About Paul Despres, NMD

Integrative Medicine & Functional Medicine & Chronic Disease in Scottsdale, AZ

Paul Despres, NMD

Paul Despres, NMD


Paul Despres, NMD, is a compassionate naturopathic medical doctor skilled in a wide variety of therapies focused on addressing the root causes of illness, empowering patients to optimal health, and emphasizing disease prevention. He practices at Nizhoni Functional Medicine, located in Scottsdale, Arizona. 

Dr. Despres earned a Bachelor of Arts in Spanish at the University of Michigan in Ann Arbor, a license in massage therapy from Bellevue Massage School, and a doctorate in naturopathic medicine from Bastyr University, most recently in 2016. Dr. Despres specializes in the diagnosis and treatment of complex, chronic illnesses, including Lyme disease and associated tick-borne infections, long Covid-19, mold disease, environmental toxicity, chronic pain, gastrointestinal disorders, SIBO, mast cell activation (MCAS), auto-immune disease, cognitive decline, and general medicine.

His personal experience working through chronic joint pain, auto-immune disease, and Lyme Disease allows Dr. Despres to emphasize with his patients’ struggles. He, too, has seen countless conventional specialists who were unable to diagnose the causes of his symptoms, nor could they offer true solutions. It was naturopathic medicine that brought answers and peace to his pain. Now, as a naturopathic medical doctor, he takes his time to get to know his patients, understand all the variables causing their symptoms, and determine which bodily systems must be restored. His clinical skills include IV therapy, clinical nutrition, botanical medicine, detox/depuration therapies, physical medicine (spinal manipulation, massage, cupping, craniosacral therapy, visceral manipulation), peptide therapy, orthomolecular medicine, mind-body medicine, low-level laser therapy, frequency-specific micro-current, and hydrotherapy. 

Dr. Despres has been a member of Nizhoni Functional Medicine since October 2021, when he moved to Tempe to support his partner Dr. Alexandra Mele, who is a first-year naturopathic medicine resident at Southwest College of Naturopathic Medicine. He has been a voting member of ILADS since 2021 and a member of GastroANP since 2021.

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